Postdoctoral Associate – LbL Nanoparticle Systems for Delivery of Cytokine Proteins for Targeted Immuno-oncology:
This position in the Paula T. Hammond lab, at the Koch Institute of Integrative Cancer Research at MIT, will be filled by a biomaterials, chemical or biomedical engineer with strong materials science, biological and/or biomedical background and expertise in animal studies and histology. The project involves a collaboration with the Darrell J. Irvine lab, and will include joint interactions across labs. Background or interest in working with both in vivo and ex vivo tumor models such as organoids, and the use of high throughput methods to discover nanoparticle function and cell-material interactions is especially encouraged. This postdoctoral associate will examine the pharmacokinetics, biodistribution and modifications of the tumor microenvironment following delivery of combinations of different cytokines, with the potential to include additional therapeutics such as immunoregulators, to address advanced serous ovarian cancer. Broader sets of collaborations may also be possible within the Koch Institute Marble Center on Nanomedicine, including those involving combination therapy nanoparticle systems, theranostic systems, and the potential to explore other modes of immuno-oncology applications using nanomaterial systems.
Paula T. Hammond, PhD
David H. Koch Chair Professor of Engineering and Department Head
Massachusetts Institute of Technology
Department of Chemical Engineering
Koch Institute of Integrative Cancer Research
Associate Editor, ACS Nano
77 Massachusetts Avenue
ChE HQ Office: Room 66-342
Koch Institute Office: Room 76-553
Cambridge, MA 02139